AG 1406
Product Specifications
UNSPSC Description
AG 1406 (compound M19) is a HER2 inhibitor, with an IC50 of 10.57 μM for HER2 in BT474 cell and >50 μM for EGFR in EGF-3T3 cell[1].
Target Antigen
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ag-1406.html
Purity
99.03
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
N#C/C(C#N)=C/C1=CC(C(C)C)=C(O)C(C(C)C)=C1
Molecular Weight
254.333
References & Citations
[1]Hui Chen, et al. Methods and compositions for inhibiting cell proliferative disorders. Patent, US5789427A.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-108931/AG-1406-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-108931/AG-1406-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
71308-34-4
Available Sizes
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