Cruzain-IN-1
Cruzain-IN-1 is a covalent and reversible Cruzain inhibitor, with an IC50 of 10 nM.
Product Specifications
CAS Number
1199523-24-4
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/Cruzain-IN-1.html
Purity
99.83
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
CCN1C2=NC(C#N)=NC(NC3=CC(F)=CC(F)=C3)=C2N=C1
Molecular Formula
C14H10F2N6
Molecular Weight
300.27
Precautions
H315, H319, H320
References & Citations
[1]Lee GM, et al. Mapping inhibitor binding modes on an active cysteine protease via nuclear magnetic resonance spectroscopy. Biochemistry. 2012 Dec 18;51 (50) :10087-98.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Trypanosoma
Available Sizes
Frequently Asked Questions
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