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Cruzain-IN-1

Cruzain-IN-1 is a covalent and reversible Cruzain inhibitor, with an IC50 of 10 nM.

Product Specifications

CAS Number

1199523-24-4

UNSPSC

12352005

Hazard Statement

H315, H319, H320

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/Cruzain-IN-1.html

Purity

99.83

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

CCN1C2=NC(C#N)=NC(NC3=CC(F)=CC(F)=C3)=C2N=C1

Molecular Formula

C14H10F2N6

Molecular Weight

300.27

Precautions

H315, H319, H320

References & Citations

[1]Lee GM, et al. Mapping inhibitor binding modes on an active cysteine protease via nuclear magnetic resonance spectroscopy. Biochemistry. 2012 Dec 18;51 (50) :10087-98.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Trypanosoma

Available Sizes

Frequently Asked Questions

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