Geissoschizoline
Geissoschizoline ((+) -Geissoschizoline) is a potent inhibitor of human AChE/BChE, with IC50s of 20.40 μM and 10.21 μM, respectively. Geissoschizoline emerges as a possible multi-target prototype that can be very useful in studies of preventing neurodegeneration and restoring neurotransmission. Geissoschizoline aiso is a potent anti-inflammatory agent[1].
Product Specifications
CAS Number
[18397-07-4]
Product Name Alternative
(+) -Geissoschizoline
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Natural Products
Related Pathways
Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Neurological Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/geissoschizoline.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1[C@@]2([H])[C@]3(C4=CC=CC=C4N2)[C@@]5([H])N(C[C@H]([C@]1([H])C5)CC)CC3
Molecular Formula
C19H26N2O
Molecular Weight
298.42
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
AChE; BChE
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