Antibiofilm agent-12
Product Specifications
UNSPSC Description
Antibiofilm agent-12 (Compound C13) is an antifungal agent that belongs to the class of carbazate derivatives. Antibiofilm agent-12 exhibits significant antifungal activity against Candida auris, with a MIC90 of 237.9 μM. By inhibiting the drug efflux pump activity of Candida auris and promoting ergosterol depletion, Antibiofilm agent-12 hinders biofilm formation and reduces the metabolic flexibility of Candida auris. Additionally, Antibiofilm agent-12 demonstrates antifungal activity in a Candida auris-infected C. elegans model[1].
Target Antigen
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antibiofilm-agent-12.html
Smiles
O=C(NNC1=CC=C(Cl)C=C1)OC2=CC=CC=C2
Molecular Weight
262.69
References & Citations
[1]Fatima T, et al. Exploring the antifungal potential of novel carbazate derivatives as promising drug candidates against emerging superbug, Candida auris. Bioorg Chem. 2024 Sep 4;153:107782.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-168077/Antibiofilm-agent-12-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-168077/
Clinical Information
No Development Reported
CAS Number
9007-83-4
Curated Selection
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