[Tyr6, D-Phe7, D-His9]-Substance P (6-11)
[Tyr6, D-Phe7, D-His9]-Substance P (6-11) is a tachykinin NK1 receptor antagonist that antagonizes Histamine induced hyperalgesia[1].
Product Specifications
CAS Number
145194-26-9
UNSPSC
12352209
Target
Neurokinin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tyr6-d-phe7-d-his9-substance-p-6-11.html
Smiles
CSCC[C@@H](C(N)=O)NC([C@H](CC(C)C)NC([C@@H](CC1=CN=CN1)NC([C@@H](NC([C@H](NC([C@@H](N)CC2=CC=C(C=C2)O)=O)CC3=CC=CC=C3)=O)CC4=CC=CC=C4)=O)=O)=O
Molecular Formula
C44H57N9O7S
Molecular Weight
856.04
References & Citations
[1]Sakurada, et al. "Possible involvement of tachykinin NK1 and NMDA receptors in histamine-induced hyperalgesia in mice." European journal of pharmacology 434.1-2 (2002) : 29-34.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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