Xanthine oxidase-IN-16

Xanthine oxidase-IN-16 is potent and orally active xanthine oxidase (XO) inhibitor with an IC50 of 102 nM. Xanthine oxidase-IN-16 shows significant efficacy in hyperuricemia rats[1].

Product Specifications

UNSPSC

12352211

Target

Xanthine Oxidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/xanthine-oxidase-in-16.html

Smiles

O=C(O)C1=CC=C(O)C(/C=C/C(C2=CC=C(NC)C=C2)=O)=C1

Molecular Formula

C17H15NO4

Molecular Weight

297.31

References & Citations

[1]Haiqi Xu, et al. Design, synthesis, and evaluation of chalcone derivatives as xanthine oxidase inhibitors. European Journal of Medicinal Chemistry. Volume 279, 5 December 2024, 116893.