Urotensin II (Human)

<strong>Urotensin II (Human)</strong> <strong>Catalog number:</strong> MDP0734 <strong>CAS Number: </strong>N/A <strong>Sequence: </strong>Glu-Thr-Pro-Asp-Cys-Phe-Trp-Lys-Tyr-Cys-Val (Disulfide bond between Cys5-Cys10) <strong>Amount:</strong> 500 ug <strong>Molecular Weight:</strong> 1388.4 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: Watanabe T, Arita S, Shiraishi Y, Suguro T, Sakai T, Hongo S, Miyazaki A. Human urotensin II promotes hypertension and atherosclerotic cardiovascular diseases Curr Med Chem. 2009;16(5):550-63. 2: Watanabe T, Kanome T, Miyazaki A, Katagiri T. Human urotensin II as a link between hypertension and coronary artery disease Hypertens Res. 2006 Jun;29(6):375-87. 3: Vaudry H, Do Rego JC, Le Mevel JC, Chatenet D, Tostivint H, Fournier A, Tonon MC, Pelletier G, Conlon JM, Leprince J. Urotensin II, from fish to human Ann N Y Acad Sci. 2010 Jul;1200:53-66. 4: Douglas SA. Human urotensin-II as a novel cardiovascular target: 'heart' of the matter or simply a fishy 'tail'? Curr Opin Pharmacol. 2003 Apr;3(2):159-67. 5: Douglas SA, Ohlstein EH. Human urotensin-II, the most potent mammalian vasoconstrictor identified to date, as a therapeutic target for the management of cardiovascular disease Trends Cardiovasc Med. 2000 Aug;10(6):229-37. 6: Russell FD, Molenaar P. Cardiovascular actions of human urotensin II--considerations for hypertension Naunyn Schmiedebergs Arch Pharmacol. 2004 Mar;369(3):271-3. 7: Katugampola SD, Maguire JJ, Kuc RE, Wiley KE, Davenport AP. Discovery of recently adopted orphan receptors for apelin, urotensin II, and ghrelin identified using novel radioligands and functional role in the human cardiovascular system Can J Physiol Pharmacol. 2002 May;80(5):369-74. 8: Jumaah S, Çelekli A, Sucu M. The role of human urotensin-II in patients with hypertrophic cardiomyopathy J Immunoassay Immunochem. 2018;39(2):150-162. 9: Lee CY, Tsai YT, Loh SH, Liu JC, Chen TH, Chao HH, Cheng TH, Chen JJ. Urotensin II induces interleukin 8 expression in human umbilical vein endothelial cells PLoS One. 2014 Feb 21;9(2):e90278. <a href="https://pubmed.ncbi.nlm.nih.gov/31874233">10: Loh SH, Chang CY, Huang SF, Chao SC, Lin WK, Huang EY, Tsai CS, Tsai YT. Functional effects of urotensin-II on intracellular pH regulators in human radial artery smooth muscle cells Peptides. 2020 Apr;126:170236. </a> <br><strong>Products Related to Urotensin II (Human) can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>