Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Brivanib (Standard)

Brivanib (Standard) is the analytical standard of Brivanib. This product is intended for research and analytical applications. Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with an IC50 of 25 nM, and has moderate potency against VEGFR-1 and FGFR-1, but >240-fold against PDGFR-β[1].

Product Specifications

Product Name Alternative

BMS-540215 (Standard)

UNSPSC

12352005

Target

Autophagy; Reference Standards; VEGFR

Type

Reference Standards

Related Pathways

Autophagy; Others; Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/brivanib-standard.html

Smiles

FC1=C(OC2=NC=NN3C2=C(C(OC[C@H](O)C)=C3)C)C=CC4=C1C=C(C)N4

Molecular Formula

C19H19FN4O3

Molecular Weight

370.38

References & Citations

[1]Bhide RS, et al. Discovery and preclinical studies of (R) -1- (4- (4-fluoro-2-methyl-1H-indol-5-yloxy) -5- methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy) propan- 2-ol (BMS-540215), an in vivo active potent VEGFR-2 inhibitor. J Med Chem, 2006, 49 (7), 2143-2146.|[2]Huynh H, et al. Brivanib alaninate, a dual inhibitor of vascular endothelial growth factor receptor and fibroblast growth factor receptor tyrosine kinases, induces growth inhibition in mouse models of human hepatocellular carcinoma. Clin Cancer Res, 2008, |[3]Nakamura I, et al. Correction: Brivanib Attenuates Hepatic Fibrosis In Vivo and Stellate Cell Activation In Vitro by Inhibition of FGF, VEGF and PDGF Signaling. PLoS One. 2015 Nov 3;10 (11) :e0142355.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-10337R/Brivanib-Standard-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-10337R/

Scientific Category

Reference Standards

CAS Number

[649735-46-6]

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

CD3e (T-Cell Marker)
MBS438059-01 0.02 mg (With BSA & Azide at 0.2mg/mL)

CD3e (T-Cell Marker)

Ask
View Details
CD3e (T-Cell Marker)
MBS438059-02 0.1 mg (With BSA & Azide at 0.2mg/mL)

CD3e (T-Cell Marker)

Ask
View Details
CD3e (T-Cell Marker)
MBS438059-03 0.1 mg (Without BSA at 1mg/mL)

CD3e (T-Cell Marker)

Ask
View Details
CD3e (T-Cell Marker)
MBS438059-04 5x 0.1 mg (With BSA & Azide at 0.2mg/mL)

CD3e (T-Cell Marker)

Ask
View Details
CD3e (T-Cell Marker)
MBS438059-05 5x 0.1 mg (Without BSA at 1mg/mL)

CD3e (T-Cell Marker)

Ask
View Details
UBXN2B Antibody, HRP conjugated
A54477-50UG 50 µg

UBXN2B Antibody, HRP conjugated

Ask
View Details