PD-1/PD-L1-IN-38
Product Specifications
UNSPSC Description
PD-1/ PD-L1-in-38 is a PD-1/PD-L1 inhibitor, which can inhibit the proliferation of tumor cells, promote the secretion of INF-γ by CD8+ T cells, and inhibit the ability of PD-1/PD-L1 signal transduction. PD-1/PD-L1-IN-38 has antitumor activity[1].
Target Antigen
PD-1/PD-L1
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pd-1-pd-l1-in-38.html
Solubility
10 mM in DMSO
Smiles
CC(C1=CC2=C(C3=C(C(C)=C(C=C3)C)C=C2)C4=C1O[C@H](OC(C)=O)[C@H](C5=CC=CC=C5)O4)C
Molecular Weight
440.53
References & Citations
[1]Li Z, et al. Discovery of Natural Ah Receptor Antagonists from Salvia miltiorrhiza Bunge and Synthesis of Analogs for Tumor Immunotherapy. J Med Chem. 2024 Jan 4.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N12537/PD-1-PD-L1-IN-38-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N12537/
Clinical Information
No Development Reported
Curated Selection
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