PD-1/PD-L1-IN-38

PD-1/ PD-L1-in-38 is a PD-1/PD-L1 inhibitor, which can inhibit the proliferation of tumor cells, promote the secretion of INF-γ by CD8+ T cells, and inhibit the ability of PD-1/PD-L1 signal transduction. PD-1/PD-L1-IN-38 has antitumor activity[1].

Product Specifications

UNSPSC

12352005

Target

PD-1/PD-L1

Type

Natural Products

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pd-1-pd-l1-in-38.html

Solubility

10 mM in DMSO

Smiles

CC(C1=CC2=C(C3=C(C(C)=C(C=C3)C)C=C2)C4=C1O[C@H](OC(C)=O)[C@H](C5=CC=CC=C5)O4)C

Molecular Formula

C29H28O4

Molecular Weight

440.53

References & Citations

[1]Li Z, et al. Discovery of Natural Ah Receptor Antagonists from Salvia miltiorrhiza Bunge and Synthesis of Analogs for Tumor Immunotherapy. J Med Chem. 2024 Jan 4.