CK1-IN-2 (hydrochloride)
CK1-IN-2 (compound Nr.4) hydrochloride is a potent CK1 inhibitor with an IC50 values of 123, 19.8, 26.8, 74.3 nM for CK1a, CK1d, CK1e, p38a, respectively[1].
Product Specifications
CAS Number
[1383377-49-8]
UNSPSC
12352005
Target
Casein Kinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ck1-in-2-hydrochloride.html
Smiles
O=C1OCC2=NC=CC(C3=CN(C)N=C3C4=CC=C(F)C=C4)=C12.[H]Cl
Molecular Formula
C17H13ClFN3O2
Molecular Weight
345.76
References & Citations
[1]Joris De Maeyer, et al. Casein kinase 1 inhibitors for use in the treatment of diseases related to dux4 expression such as muscular dystrophy and cancer. WO2020249717A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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