P-orlandin
P-orlandin, a fungal metabolite, prevents FREP1 from binding to gametocytes or ookinetes. P-orlandin effectively inhibits P. falciparum infection in mosquitoes[1].
Product Specifications
CAS Number
[1407546-21-7]
UNSPSC
12352005
Target
Endogenous Metabolite; Parasite
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/p-orlandin.html
Solubility
10 mM in DMSO
Smiles
O=C1OC2=C(C(OC)=C1)C(C)=CC(O)=[C@]2[C@](C(O)=CC(C)=C3C(OC)=C4)=C3OC4=O
Molecular Formula
C22H18O8
Molecular Weight
410.37
References & Citations
[1]Niu G, et al. Targeting mosquito FREP1 with a fungal metabolite blocks malaria transmission. Sci Rep. 2015;5:14694. Published 2015 Oct 6.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Microbial Metabolite; Plasmodium
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