NG-012
NG-012, potentiator of nerve growth factor (NGF), were isolated from the culture broth of Penicillium verruculosum F-4542. NG-012 potentiates the neurite outgrowth induced by NGF in rat pheochromocytoma cell line (PC12) [1].
Product Specifications
CAS Number
141731-76-2
Product Name Alternative
eFT508
UNSPSC
12352005
Target
Trk Receptor
Type
Natural Products
Related Pathways
Neuronal Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ng-012.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(O)C=C(O)C=C1C[C@@H](C)OC(C[C@@H](C)O2)=O)O[C@H](C)CC(O[C@H](CO)CC(O[C@H](C)CC3=CC(O)=CC(O)=C3C2=O)=O)=O
Molecular Formula
C32H38O15
Molecular Weight
662.64
References & Citations
[1]M Ito, et al. NG-011 and NG-012, novel potentiators of nerve growth factor. II. The structure determination of NG-011 and NG-012. J Antibiot (Tokyo) . 1992 Oct;45 (10) :1566-72.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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