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NG-012

NG-012, potentiator of nerve growth factor (NGF), were isolated from the culture broth of Penicillium verruculosum F-4542. NG-012 potentiates the neurite outgrowth induced by NGF in rat pheochromocytoma cell line (PC12) [1].

Product Specifications

CAS Number

141731-76-2

Product Name Alternative

eFT508

UNSPSC

12352005

Target

Trk Receptor

Type

Natural Products

Related Pathways

Neuronal Signaling; Protein Tyrosine Kinase/RTK

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ng-012.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=C(O)C=C(O)C=C1C[C@@H](C)OC(C[C@@H](C)O2)=O)O[C@H](C)CC(O[C@H](CO)CC(O[C@H](C)CC3=CC(O)=CC(O)=C3C2=O)=O)=O

Molecular Formula

C32H38O15

Molecular Weight

662.64

References & Citations

[1]M Ito, et al. NG-011 and NG-012, novel potentiators of nerve growth factor. II. The structure determination of NG-011 and NG-012. J Antibiot (Tokyo) . 1992 Oct;45 (10) :1566-72.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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