VMY-2-95
Product Specifications
UNSPSC Description
VMY-2-95 is an oral active and blood-brain barrier (BBB) penetrant α4β2 nicotinic acetylcholine receptor desensitizer. VMY-2-95 can be used for study of depression or addiction[1][2].
Target Antigen
nAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/vmy-2-95.html
Smiles
C1(OC[C@@H]2CCN2)=CC(C#CC3=CC=CC=C3)=CN=C1
Molecular Weight
264.32
References & Citations
[1]Kong H, et al. Preclinical studies of the potent and selective nicotinic α4β2 receptor ligand VMY-2-95. Mol Pharm. 2015;12(2):393-402. |[2]Yenugonda VM, et al. Design, synthesis and discovery of picomolar selective α4β2 nicotinic acetylcholine receptor ligands. J Med Chem. 2013;56(21):8404-8421.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-120946/VMY-2-95-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-120946/
Clinical Information
No Development Reported
CAS Number
1434047-61-6
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
