CSF1R-IN-20
CSF1R-IN-20 (compound 7a) is a CSF-1R Inhibitor with an IC50 value of 467 nM. CSF1R-IN-20 inhibits CSF-1R auto-phosphorylation[1].
Product Specifications
CAS Number
2935479-57-3
UNSPSC
12352005
Target
C-Fms
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/csf1r-in-20.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=NOC(C)=C1)NC2=CC(NC(C3=CC(C(F)(F)F)=CC(N4CCN(C)CC4)=C3)=O)=CC=C2C
Molecular Formula
C25H26F3N5O3
Molecular Weight
501.50
References & Citations
[1]Jihyun Baek, et al. Discovery of N- (5-amido-2-methylphenyl) -5-methylisoxazole-3-carboxamide as dual CSF-1R/c-Kit Inhibitors with improved stability and BBB permeability. Eur J Med Chem. 2024 Feb 20:268:116253.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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