Ginkgolic Acid (Standard)
Ginkgolic Acid (Standard) is the analytical standard of Ginkgolic Acid. This product is intended for research and analytical applications. Ginkgolic Acid is a natural compound that inhibits SUMOylation with an IC50 of 3.0 μM in in vitro assay.
Product Specifications
CAS Number
22910-60-7
Product Name Alternative
Ginkgolic acid (15:1) (Standard) ; Ginkgolic acid I (Standard) ; Romanicardic acid (Standard)
UNSPSC
12352005
Target
E1/E2/E3 Enzyme; Reference Standards
Type
Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ginkgolic-acid-standard.html
Smiles
O=C(O)C1=C(CCCCCCC/C=C\CCCCCC)C=CC=C1O
Molecular Formula
C22H34O3
Molecular Weight
346.50
References & Citations
[1]Fukuda I, et al. Ginkgolic acid inhibits protein SUMOylation by blocking formation of the E1-SUMO intermediate. Chem Biol. 2009 Feb 27;16 (2) :133-40.|[2]Lü JM, et al. Ginkgolic acid inhibits HIV protease activity and HIV infection in vitro. Med Sci Monit. 2012 Aug;18 (8) :BR293-298.|[3]Zhou C, et al. Antitumor effects of ginkgolic acid in human cancer cell occur via cell cycle arrest and decrease the Bcl-2/Bax ratio to induce apoptosis. Chemotherapy. 2010;56 (5) :393-402.|[4]Qiu F, et al. Pharmacological inhibition of SUMO-1 with ginkgolic acid alleviates cardiac fibrosis induced by myocardial infarction in mice. Toxicol Appl Pharmacol. 2018 Apr 15;345:1-9.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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