Phospho-MCM2 (Ser139) Rabbit mAb APC Conjugate

<strong>Phospho-MCM2 (Ser139) Rabbit mAb APC Conjugate</strong>_x000D_ <strong>Catalog number:</strong> B2018545_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 25 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8°C_x000D_ <strong>Keywords:</strong> DNA replication licensing factor MCM2, Minichromosome maintenance protein 2 homolog, Nuclear protein BM28, CCNL1, CDCL1, KIAA0030_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Bastia D, Srivastava P, Zaman S, Choudhury M, Mohanty BK, Bacal J, Langston LD, Pasero P, O'Donnell ME. Phosphorylation of CMG helicase and Tof1 is required for programmed fork arrest Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):E3639-48._x000D_ 2: Wang X, Ishimi Y. Function of the amino-terminal region of human MCM4 in helicase activity J Biochem. 2018 Dec 1;164(6):449-460._x000D_ 3: Cho WH, Lee YJ, Kong SI, Hurwitz J, Lee JK. CDC7 kinase phosphorylates serine residues adjacent to acidic amino acids in the minichromosome maintenance 2 protein Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11521-6._x000D_ 4: Cattaneo F, Russo R, Castaldo M, Chambery A, Zollo C, Esposito G, Pedone PV, Ammendola R. Phosphoproteomic analysis sheds light on intracellular signaling cascades triggered by Formyl-Peptide Receptor 2 Sci Rep. 2019 Nov 29;9(1):17894._x000D_ 5: Liang Y, Su Y, Xu C, Zhang N, Liu D, Li G, Tong T, Chen J. Protein kinase D1 phosphorylation of KAT7 enhances its protein stability and promotes replication licensing and cell proliferation Cell Death Discov. 2020 Sep 18;6(1):89._x000D_ 6: Wang Z, Wang Y, He Y, Zhang N, Chang W, Niu Y. Aquaporin-1 facilitates proliferation and invasion of gastric cancer cells via GRB7-mediated ERK and Ras activation Anim Cells Syst (Seoul). 2020 Oct 21;24(5):253-259._x000D_ 7: Maros ME, Balla P, Micsik T, Sapi Z, Szendroi M, Wenz H, Groden C, Forsyth RG, Picci P, Krenacs T. Cell Cycle Regulatory Protein Expression in Multinucleated Giant Cells of Giant Cell Tumor of Bone: do They Proliferate? Pathol Oncol Res. 2021 May 3;27:643146._x000D_ 8: Mimura S, Seki T, Tanaka S, Diffley JF. Phosphorylation-dependent binding of mitotic cyclins to Cdc6 contributes to DNA replication control Nature. 2004 Oct 28;431(7012):1118-23._x000D_ 9: Margraf LR, Gargan L, Butt Y, Raghunathan N, Bowers DC. Proliferative and metabolic markers in incompletely excised pediatric pilocytic astrocytomas--an assessment of 3 new variables in predicting clinical outcome Neuro Oncol. 2011 Jul;13(7):767-74._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/17046832">10: Masai H, Taniyama C, Ogino K, Matsui E, Kakusho N, Matsumoto S, Kim JM, Ishii A, Tanaka T, Kobayashi T, Tamai K, Ohtani K, Arai K. Phosphorylation of MCM4 by Cdc7 kinase facilitates its interaction with Cdc45 on the chromatin J Biol Chem. 2006 Dec 22;281(51):39249-61. </a>_x000D_ _x000D_ <strong>Products Related to Phospho-MCM2 (Ser139) Rabbit mAb APC Conjugate can be found at</strong> <a href="https://moleculardepot.com/product-category/Conjugates/"> Conjugates</a>