5-Ph-IAA
Product Specifications
UNSPSC Description
5-Ph-IAA is a derivative of IAA. 5-Ph-IAA, a ligand, establishes the auxin-inducible degron 2 (AID2) system together with an OsTIR1 (F74G) mutant. AID2 induces rapid and efficient depletion of mAID-fused proteins to study protein function in living cells, causing tumor suppression[1].
Target Antigen
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/5-ph-iaa.html
Smiles
O=C(O)CC1=CNC2=C1C=C(C3=CC=CC=C3)C=C2
Molecular Weight
251.28
References & Citations
[1]Aisha Yesbolatova, et al. The auxin-inducible degron 2 technology provides sharp degradation control in yeast, mammalian cells, and mice. Nat Commun. 2020 Nov 11;11(1):5701.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-134653/5-Ph-IAA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-134653/5-Ph-IAA-SDS-MedChemExpress.pdf
CAS Number
168649-23-8
Available Sizes
Curated Selection
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