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5-Ph-IAA

Product Specifications

UNSPSC Description

5-Ph-IAA is a derivative of IAA. 5-Ph-IAA, a ligand, establishes the auxin-inducible degron 2 (AID2) system together with an OsTIR1 (F74G) mutant. AID2 induces rapid and efficient depletion of mAID-fused proteins to study protein function in living cells, causing tumor suppression[1].

Target Antigen

Epigenetic Reader Domain

Type

Reference compound

Related Pathways

Epigenetics

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/5-ph-iaa.html

Smiles

O=C(O)CC1=CNC2=C1C=C(C3=CC=CC=C3)C=C2

Molecular Weight

251.28

References & Citations

[1]Aisha Yesbolatova, et al. The auxin-inducible degron 2 technology provides sharp degradation control in yeast, mammalian cells, and mice. Nat Commun. 2020 Nov 11;11(1):5701.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-134653/5-Ph-IAA-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-134653/5-Ph-IAA-SDS-MedChemExpress.pdf

CAS Number

168649-23-8

Available Sizes

Curated Selection

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