AZD-1678
AZD-1678 is a potent CCR4 receptor antagonist, with a pIC50 of 8.6[1].
Product Specifications
CAS Number
[942137-41-9]
UNSPSC
12352005
Hazard Statement
H302, H373
Target
CCR
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/azd-1678.html
Purity
98.12
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=S(C1=CC=CC(Cl)=C1Cl)(NC2=NC=C(F)N=C2OC)=O
Molecular Formula
C11H8Cl2FN3O3S
Molecular Weight
352.17
Precautions
H302, H373
References & Citations
[1]Nicholas Kindon, et al. Discovery of AZD-2098 and AZD-1678, Two Potent and Bioavailable CCR4 Receptor Antagonists. ACS Med Chem Lett. 2017 Sep 1;8 (9) :981-986.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CCR4
Available Sizes
Curated Selection
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