SS-208
Product Specifications
Product Name Alternative
AVS100
UNSPSC Description
SS-208 is a selective HDAC6 inhibitor, with an IC50 of 12 nM. SS-208 possesses anti-tumor activity in melanoma[1].
Target Antigen
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Epigenetics
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ss-208.html
Purity
99.00
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(C1=NOC(CCNC(C2=CC=C(Cl)C(Cl)=C2)=O)=C1)NO
Molecular Weight
344.15
References & Citations
[1]Shen S, et al. Discovery of a New Isoxazole-3-hydroxamate-Based Histone Deacetylase 6 Inhibitor SS-208 with Antitumor Activity in Syngeneic Melanoma Mouse Models. J Med Chem. 2019 Sep 4.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-126330/SS-208-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-126330/SS-208-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2245942-72-5
Available Sizes
Curated Selection
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