DNA PKcs (Phospho-Ser2056) Rabbit mAb [KD Validated] Antibody
The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK) . The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.
Product Specifications
Product Name Alternative
DNA- PKcs, DNA-dependent protein kinase catalytic subunit, DNPK1, EC 2.7.11.1, P460, PRKD, PRKDC, XRCC7, kinase DNA-PK
UniProt
P78527
Reactivity
Human
Immunogen
A synthesized peptide derived from human Phospho-DNA PKcs (S2056)
Clonality
Monoclonal
Conjugation
Unconjugated
Source
Recombinant Rabbit
Field of Research
Signal Transduction
Purification
Affinity-chromatography
Dilution
WB:1:500~1:2000IHC:1:50~1:200ICC/IF:1:50~1:200
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Molecular Weight
469kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ICC, IHC, WB
Host or Source
Rabbit
Isotype
Rabbit IgG
Available Sizes
Frequently Asked Questions
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