PBK/TOPK (Phospho-Thr9) Rabbit mAb [KD Validated] Antibody
Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage.
Product Specifications
Product Name Alternative
CT84; MAPKK like protein kinase; Nori3; PBK; PDZ binding kinas; Serine/threonine protein kinase; SPK; TOPK
UniProt
Q96KB5
Reactivity
Human
Immunogen
A synthesized peptide derived from human Phospho-PBK/TOPK (Thr9)
Clonality
Monoclonal
Conjugation
Unconjugated
Source
Recombinant Rabbit
Field of Research
Cancer Biology
Purification
Affinity-chromatography
Dilution
WB:1:500~1:2000IHC:1:50~1:200
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Molecular Weight
40kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
IHC, WB
Host or Source
Rabbit
Isotype
Rabbit IgG
Available Sizes
Frequently Asked Questions
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