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PBK/TOPK (Phospho-Thr9) Rabbit mAb [KD Validated] Antibody

Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage.

Product Specifications

Product Name Alternative

CT84; MAPKK like protein kinase; Nori3; PBK; PDZ binding kinas; Serine/threonine protein kinase; SPK; TOPK

UniProt

Q96KB5

Reactivity

Human

Immunogen

A synthesized peptide derived from human Phospho-PBK/TOPK (Thr9)

Clonality

Monoclonal

Conjugation

Unconjugated

Source

Recombinant Rabbit

Field of Research

Cancer Biology

Purification

Affinity-chromatography

Dilution

WB:1:500~1:2000IHC:1:50~1:200

Form

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Molecular Weight

40kDa

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Tested Applications

IHC, WB

Host or Source

Rabbit

Isotype

Rabbit IgG

Available Sizes

Frequently Asked Questions

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