(2-Hydroxypropyl) -γ-cyclodextrin (Highly Pure)

<strong>(2-Hydroxypropyl)-γ-cyclodextrin (Highly Pure)</strong>_x000D_ <strong>Catalog number:</strong> B2010647_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 g_x000D_ <strong>Molecular Weight or Concentration:</strong> na_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> solubilizing agent and versatile molecular tool for various applications_x000D_ <strong>Storage:</strong> RT_x000D_ <strong>Keywords:</strong> (2-hydroxypropyl)-gamma-cyclodextrin, HGC, 2-OH-gamma cyclodextrin_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Singhal A, Krystofiak ES, Jerome WG, Song B. 2-Hydroxypropyl-gamma-_x000D_ cyclodextrin overcomes NPC1 deficiency by enhancing lysosome-ER association and_x000D_ autophagy. Sci Rep. 2020 May 26;10(1):8663._x000D_ _x000D_ 2: Hollow SE, Johnstone TC. Encapsulation of <i>closo</i>-dodecaiodododecaborate_x000D_ in 2-hydroxypropyl-γ-cyclodextrin prevents hemolysis. Chem Commun (Camb). 2022_x000D_ Jan 26._x000D_ _x000D_ 3: Hoque S, Kondo Y, Sakata N, Yamada Y, Fukaura M, Higashi T, Motoyama K, Arima_x000D_ H, Higaki K, Hayashi A, Komiya T, Ishitsuka Y, Irie T. Differential Effects of_x000D_ 2-Hydroxypropyl-Cyclodextrins on Lipid Accumulation in <i>Npc1</i>-Null Cells._x000D_ Int J Mol Sci. 2020 Jan 30;21(3):898._x000D_ _x000D_ 4: Sursyakova VV, Levdansky VA, Rubaylo AI. Strong complexation of water-soluble_x000D_ betulin derivatives with (2-hydroxypropyl)-γ-cyclodextrin studied by affinity_x000D_ capillary electrophoresis. Electrophoresis. 2020 Jan;41(1-2):112-115._x000D_ _x000D_ 5: Huang H, Tang G, Wang Q, Li D, Shen F, Zhou J, Yu H. Two novel non-viral gene_x000D_ delivery vectors: low molecular weight polyethylenimine cross-linked by_x000D_ (2-hydroxypropyl)-beta-cyclodextrin or (2-hydroxypropyl)-gamma-cyclodextrin._x000D_ Chem Commun (Camb). 2006 Jun 14;(22):2382-4._x000D_ _x000D_ 6: Yamada Y, Ishitsuka Y, Kondo Y, Nakahara S, Nishiyama A, Takeo T, Nakagata N,_x000D_ Motoyama K, Higashi T, Arima H, Kamei S, Shuto T, Kai H, Hayashino Y, Sugita M,_x000D_ Kikuchi T, Hirata F, Miwa T, Takeda H, Orita Y, Seki T, Ohta T, Kurauchi Y,_x000D_ Katsuki H, Matsuo M, Higaki K, Ohno K, Matsumoto S, Era T, Irie T. Differential_x000D_ mode of cholesterol inclusion with 2-hydroxypropyl-cyclodextrins increases_x000D_ safety margin in treatment of Niemann-Pick disease type C. Br J Pharmacol. 2021_x000D_ Jul;178(13):2727-2746._x000D_ _x000D_ 7: Blum W, Aichholz R, Ramstein P, Fetz A, Raschdorf F. Determination of_x000D_ 2-hydroxypropyl-gamma-cyclodextrin in plasma of cynomolgus monkeys after oral_x000D_ administration by gas chromatography-mass spectrometry. J Chromatogr B Biomed_x000D_ Sci Appl. 1998 Dec 11;720(1-2):171-8._x000D_ 8: Wathoni N, Motoyama K, Higashi T, Okajima M, Kaneko T, Arima H. Enhancement_x000D_ of curcumin wound healing ability by complexation with 2-hydroxypropyl-γ-_x000D_ cyclodextrin in sacran hydrogel film. Int J Biol Macromol. 2017 May;98:268-276._x000D_ _x000D_ 9: Trapani G, Latrofa A, Franco M, Pantaleo MR, Sanna E, Massa F, Tuveri F, Liso_x000D_ G. Complexation of zolpidem with 2-hydroxypropyl-beta-, methyl-beta-, and_x000D_ 2-hydroxypropyl-gamma-cyclodextrin: effect on aqueous solubility, dissolution_x000D_ rate, and ataxic activity in rat. J Pharm Sci. 2000 Nov;89(11):1443-51._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/29607998/">10: Motoyama K, Higashi T, Okajima MK, Kaneko T, Arima H. [Potential Use of_x000D_ Sacran Hydrogels as Wound Dressing Material]. Yakugaku Zasshi._x000D_ 2018;138(4):517-520. </a>_x000D_ _x000D_ <strong>Products Related to (2-Hydroxypropyl)-γ-cyclodextrin (Highly Pure)</strong><a href="https://moleculardepot.com/product-category/Chemicals/">: Chemicals</a>