GBP4, mouse (HEK293, His)
GBP4, an IFN-inducible GTPase, crucially defends against various pathogens.It hydrolyzes GTP to GDP and aids inflammasome assembly by releasing ligands from bacteria.GBP4 promotes pathogen-containing vacuole lysis, facilitating cytosolic entry, where it recruits proteins like Gm12250/Irgb10 for bacterial cytolysis.This liberation activates inflammasomes, including CASP4/CASP11 and AIM2.GBP4 may also influence erythroid differentiation.GBP4 protein, mouse (HEK293, His) is the recombinant mouse-derived GBP4 protein, expressed by HEK293 , with N-8*His labeled tag.
Product Specifications
Product Name Alternative
GBP4 protein, Mouse (HEK293, His), Mouse, HEK293
UNSPSC
12352202
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/gbp4-protein-mouse-hek293-his.html
Purity
90.0
Smiles
Molecular Formula
55932 (Gene_ID) Q61107 (E2-S620) (Accession)
Molecular Weight
Approximately 73.8 kDa
Shipping Conditions
Room temperature in continental US; may vary elsewhere.
Storage Conditions
Stored at -20°C for 2 years
Scientific Category
Recombinant Proteins
Frequently Asked Questions
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