Epeleuton-d5
Product Specifications
UNSPSC Description
Epeleuton-d5 (15(S)-HEPE-d5 ethyl ester) is deuterium labeled Epeleuton. Epeleuton is a second-generation synthetic N-3 fatty acid derivative with activity in patients with non-alcoholic fatty liver disease, although it did not reach the primary endpoints of alanine aminotransferase and liver stiffness, but it can significantly reduce triglycerides, glycated hemoglobin, plasma glucose and inflammatory markers[1].
Target Antigen
Isotope-Labeled Compounds; Others
Type
Isotope-Labeled Compounds
Related Pathways
Others
Field of Research
Others
Smiles
O[C@H](/C=C/C=C\C/C=C\C/C=C\CCCC(OCC)=O)C/C=C\C([2H])(C([2H])([2H])[2H])[2H]
Molecular Weight
351.53
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Effects of Epeleuton, a Novel Synthetic Second-Generation n-3 Fatty Acid, on Non-Alcoholic Fatty Liver Disease, Triglycerides, Glycemic Control, and Cardiometabolic and Inflammatory Markers
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
Curated Selection
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