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NH2-AKK-COOH

Product Specifications

UNSPSC Description

NH2-AKK-COOH, a synthetic tripeptide, is an ACE inhibitor, with IC50s of 0.090 μM, 0.178 μM, and 420.89 μM when FAPGG, HHL, and angiotensin-I are used as substrate respectively[1].

Target Antigen

Angiotensin-converting Enzyme (ACE)

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/nh2-akk-cooh.html

Solubility

H2O

Smiles

O=C(N[C@H](C(O)=O)CCCCN)[C@H](CCCCN)NC([C@@H](N)C)=O

Molecular Weight

345.44

References & Citations

[1]Henda YB, et, al. Measuring angiotensin-I converting enzyme inhibitory activity by micro plate assays: comparison using marine cryptides and tentative threshold determinations with captopril and losartan. J Agric Food Chem. 2013 Nov 13;61(45):10685-90.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P3424/NH2-AKK-COOH-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P3424/

Clinical Information

No Development Reported

CAS Number

158837-92-4

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