NH2-AKK-COOH

NH2-AKK-COOH, a synthetic tripeptide, is an ACE inhibitor, with IC50s of 0.090 μM, 0.178 μM, and 420.89 μM when FAPGG, HHL, and angiotensin-I are used as substrate respectively[1].

Product Specifications

CAS Number

[158837-92-4]

UNSPSC

12352209

Target

Angiotensin-converting Enzyme (ACE)

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/nh2-akk-cooh.html

Solubility

H2O

Smiles

O=C(N[C@H](C(O)=O)CCCCN)[C@H](CCCCN)NC([C@@H](N)C)=O

Molecular Formula

C15H31N5O4

Molecular Weight

345.44

References & Citations

[1]Henda YB, et, al. Measuring angiotensin-I converting enzyme inhibitory activity by micro plate assays: comparison using marine cryptides and tentative threshold determinations with captopril and losartan. J Agric Food Chem. 2013 Nov 13;61 (45) :10685-90.