NH2-AKK-COOH
NH2-AKK-COOH, a synthetic tripeptide, is an ACE inhibitor, with IC50s of 0.090 μM, 0.178 μM, and 420.89 μM when FAPGG, HHL, and angiotensin-I are used as substrate respectively[1].
Product Specifications
CAS Number
158837-92-4
UNSPSC
12352209
Target
Angiotensin-converting Enzyme (ACE)
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/nh2-akk-cooh.html
Solubility
H2O
Smiles
O=C(N[C@H](C(O)=O)CCCCN)[C@H](CCCCN)NC([C@@H](N)C)=O
Molecular Formula
C15H31N5O4
Molecular Weight
345.44
References & Citations
[1]Henda YB, et, al. Measuring angiotensin-I converting enzyme inhibitory activity by micro plate assays: comparison using marine cryptides and tentative threshold determinations with captopril and losartan. J Agric Food Chem. 2013 Nov 13;61 (45) :10685-90.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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