H4R antagonist 3
H4R antagonist 3 (Example 18) is a histamine-4 receptor antagonist with an EC50 of [1].
Product Specifications
CAS Number
[1003091-20-0]
UNSPSC
12352005
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/h4r-antagonist-3.html
Purity
96.29
Solubility
DMSO : 2 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
ClC1=CC=C(C2=CSC3=NC=NC(N(C4CCN(CC4)C)C)=C32)C=C1
Molecular Formula
C19H21ClN4S
Molecular Weight
372.91
References & Citations
[1]Allen J. Borchardt, et al. Aminopyrimidine inhibitors of histamine receptors for the treatment of disease. Patent US20100063047A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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