Human Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer Protein, His Tag&Tag Free
Selected Variant
IT2-H53W3-1mg
Size: 1 mg
Integrin alpha-L beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin alpha L beta 2 is also a receptor for F11R (By similarity) . Involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. Contributes to natural killer cell cytotoxicity. Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils. Required for generation of common lymphoid progenitor cells in bone marrow, indicating the role in lymphopoiesis. Integrin alpha L beta 2 in association with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages.
Product Specifications
Background
Specifications
Accession Number
P20701-1 (ITGAL) & P05107-1 (ITGB2)
Expression Region
Tyr 26 - Met 1089 (ITGAL) & Gln 23 - Asn 700 (ITGB2)
Host
CHO
Target
Integrin alpha L beta 2
Conjugation
Unconjugated
Tag
C-10xHis | Native
Source
Human
Stability
Endotoxin
1.0 EU per μg
Purity
95%
Bioactivity
Format
Powder
Buffer
50 mM Tris, 150 mM NaCl, pH7.5
Additives
Trehalose
Molecular Weight
124.1 kDa | 80.2 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
500ug*2
Host or Source
CHO
Species
Human
Protein ID
P20701-1 (ITGAL) & P05107-1 (ITGB2)
Preservative
Trehalose
Price
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