Phospho-CrkL (Y207) Recombinant Rabbit Monoclonal Antibody [JE55-58]
Selected Variant
HA721675
Size: 100 µL
Crk-like protein is a protein that in humans is encoded by the CRKL gene. v-CRK avian sarcoma virus CT10-homolog-like contains one SH2 domain and two SH3 domains. CRKL has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase and plays a role in fibroblast transformation by BCR-ABL. In addition, CRKL has oncogenic potential. CrkL together with Crk participates in the Reelin signaling cascade downstream of DAB1.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
CRKL
Swiss Prot
P46109 Human, P47941 Mouse, Q5U2U2 Rat
Cellular Locus
cytosol, extrinsic component of postsynaptic membrane, neuromuscular junction, nucleoplasm, protein-containing complex.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic phosphopeptide corresponding to residues surrounding Tyr207 of human CrkL protein.
Isotype
IgG
Clone
JE55-58
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
K-562 cell lysate.
Concentration
1 mg/mL
Dilution
WB: 1:2,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 34 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Price
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
HIF1 alpha (Hypoxia-Inducible Factor 1-alpha) (ESEE122), CF405S conjugate, 0.1mg/mL
![Mouse PD-L1 Recombinant Rabbit Monoclonal Antibody [PSH04-84] - BSA and Azide free (Detector)](https://cdn.genprice.uk/products/992/68dd1c8c061270361ea81d75/imageurl/ha722190.webp)
Mouse PD-L1 Recombinant Rabbit Monoclonal Antibody [PSH04-84] - BSA and Azide free (Detector)
Anti-LGI4 Antibody Picoband®, Cy3 Conjugate
MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2278R), CF488A conjugate, 0.1mg/mL
![ABAT / GABA-T Recombinant Rabbit Monoclonal Antibody [JE50-16]](https://cdn.genprice.uk/products/992/68dd1c8d061270361ea820c5/imageurl/et7110-01.webp)