Tigolaner
Tigolaner (BAY-1272858) acts on γ-aminobutyric acid (GABA) and glutamate-gated chloride channels. Tigolaner has antiparasitic activity[1].
Product Specifications
CAS Number
1621436-41-6
Product Name Alternative
BAY-1272858
UNSPSC
12352005
Target
Chloride Channel; GABA Receptor; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Infection; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tigolaner.html
Concentration
10mM
Purity
98.53
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
FC(F)(C(C(C(F)(F)C(F)(F)F)=N1)=C(N2C=C(C(C=C3)=CC(C(NC4(CC4)C#N)=O)=C3Cl)C=N2)N1C)F
Molecular Formula
C21H13ClF8N6O
Molecular Weight
552.81
References & Citations
[1]Mencke N, et al. Plasma pharmacokinetics of tigolaner, emodepside, and praziquantel following topical administration of a combination product (Felpreva®) and of intravenous administration of the individual active ingredients in cats. Curr Res Parasitol Vector Borne Dis. 2023 Jun 22;4:100126.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
bs-10071R-BF594 100 µL
VEGFB167 Polyclonal Antibody, AbBy Fluor™ 594 Conjugated
Sign In for Pricing
View Details 
GTR15185708 1 Vial
Lentiviral mouse Cacna1h shRNA (UAS) - Lentiviral mouseCacna1h shRNA (UAS, GFP) (25)
Sign In for Pricing
View Details 