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Tigolaner

Tigolaner (BAY-1272858) acts on γ-aminobutyric acid (GABA) and glutamate-gated chloride channels. Tigolaner has antiparasitic activity[1].

Product Specifications

CAS Number

[1621436-41-6]

Product Name Alternative

BAY-1272858

UNSPSC

12352005

Target

Chloride Channel; GABA Receptor; Parasite

Type

Reference compound

Related Pathways

Anti-infection; Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Infection; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/tigolaner.html

Concentration

10mM

Purity

98.53

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

FC(F)(C(C(C(F)(F)C(F)(F)F)=N1)=C(N2C=C(C(C=C3)=CC(C(NC4(CC4)C#N)=O)=C3Cl)C=N2)N1C)F

Molecular Formula

C21H13ClF8N6O

Molecular Weight

552.81

References & Citations

[1]Mencke N, et al. Plasma pharmacokinetics of tigolaner, emodepside, and praziquantel following topical administration of a combination product (Felpreva®) and of intravenous administration of the individual active ingredients in cats. Curr Res Parasitol Vector Borne Dis. 2023 Jun 22;4:100126.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light, stored under nitrogen)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-109077/Tigolaner-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-109077/Tigolaner-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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