Mpro/Cathepsin L-IN-1
Mpro/Cathepsin L-IN-1 (Compound 4d) is a SARS-CoV-2 Mpro/hCatL inhibitor, with Kis of 5.54 μM and 0.701 μM respectively[1].
Product Specifications
UNSPSC
12352005
Target
Cathepsin; SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mpro-cathepsin-l-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](CC(C)(C)C)C(N[C@H](/C=C/C(C)=O)C[C@H]1C(NCC1)=O)=O)C2=CC=C(F)C=C2
Molecular Formula
C24H32FN3O4
Molecular Weight
445.53
References & Citations
[1]Santo Previti, et al. Identification of Dual Inhibitors Targeting Main Protease (Mpro) and Cathepsin L as Potential Anti-SARS-CoV-2 Agents. ACS Med. Chem. Lett. 2024
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cathepsin L
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