U0124
Product Specifications
UNSPSC Description
U0124, an inactive U0126 analog, has no effect on c-Fos and c-Jun protein or mRNA levels. U0126 is a MEK inhibitor. U0124 does not inhibit MEK at concentrations up to 100 μM[1].
Target Antigen
MEK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/u0124.html
Purity
98.0
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
N#CC(/C(C#N)=C(N)/SC)=C(N)\SC
Molecular Weight
226.32
References & Citations
[1]M F Favata, et al. Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J Biol Chem. 1998 Jul 17;273(29):18623-32.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-107621/U0124-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-107621/U0124-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
108923-79-1
Available Sizes
Curated Selection
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