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AR-M1896

AR-M1896 is a GalR2 selective agonist with a binding IC50 of 1.76 nM for rat GalR2. AR-M1896 can be used for the research of acute myocardial infarction and neuropathic pain[1][2].

Product Specifications

CAS Number

367518-31-8

UNSPSC

12352209

Target

Neuropeptide Y Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ar-m1896.html

Solubility

10 mM in DMSO

Smiles

OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CC(C)C)=O)=O)NC(CNC([C@H](C)NC([C@H](CO)NC([C@H](CC(N)=O)NC([C@H](CC(C)C)NC([C@@]([C@H](O)C)([H])NC([C@@H](N)CC2=CNC3=CC=CC=C23)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C54H81N13O14

Molecular Weight

1136.30

References & Citations

[1]Liu HX, et al. Receptor subtype-specific pronociceptive and analgesic actions of galanin in the spinal cord: selective actions via GalR1 and GalR2 receptors. Proc Natl Acad Sci U S A. 2001 Aug 14;98 (17) :9960-4.|[2]Serebryakova L, et al. Galanin and its N-terminal fragments reduce acute myocardial infarction in rats. Peptides. 2019 Jan;111:127-131.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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