(Rac) -Shikonin
(Rac) -Shikonin (Shikonin) possesses anti-tumor activity. (Rac) -Shikonin (Shikonin) circumvents cancer agent resistance by induction of a necroptotic death[1][2].
Product Specifications
CAS Number
[54952-43-1]
Product Name Alternative
Shikalkin
UNSPSC
12352005
Hazard Statement
H302, H400
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rac-shikonin.html
Purity
98.95
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
OC1=C2C(C(C=C(C(C/C=C(C)/C)O)C2=O)=O)=C(O)C=C1
Molecular Formula
C16H16O5
Molecular Weight
288.30
Precautions
H302, H400
References & Citations
[1]U Sankawa, Antitumor activity of shikonin and its derivatives. Chem Pharm Bull (Tokyo) . 1977 Sep;25 (9) :2392-5.|[2]Weidong Han, et al. Shikonin circumvents cancer drug resistance by induction of a necroptotic death. Mol Cancer Ther. 2007 May;6 (5) :1641-9.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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