(Rac) -Shikonin

(Rac) -Shikonin (Shikonin) possesses anti-tumor activity. (Rac) -Shikonin (Shikonin) circumvents cancer agent resistance by induction of a necroptotic death[1][2].

Product Specifications

CAS Number

[54952-43-1]

Product Name Alternative

Shikalkin

UNSPSC

12352005

Hazard Statement

H302, H400

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/rac-shikonin.html

Purity

98.95

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

OC1=C2C(C(C=C(C(C/C=C(C)/C)O)C2=O)=O)=C(O)C=C1

Molecular Formula

C16H16O5

Molecular Weight

288.30

Precautions

H302, H400

References & Citations

[1]U Sankawa, Antitumor activity of shikonin and its derivatives. Chem Pharm Bull (Tokyo) . 1977 Sep;25 (9) :2392-5.|[2]Weidong Han, et al. Shikonin circumvents cancer drug resistance by induction of a necroptotic death. Mol Cancer Ther. 2007 May;6 (5) :1641-9.