Caspase-6 Substrate III Fluorogenic

<strong>Caspase-6 Substrate III Fluorogenic</strong>_x000D_ <strong>Catalog number:</strong> B2014281_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 2 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 819.78 g/mol_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −20°C_x000D_ <strong>Keywords:</strong> Caspase-6 Substrate III, Fluorogenic_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Huang S, Mei H, Lu L, Kuang Z, Heng Y, Xu L, Liang X, Qiu M, Pan X. Conformational transitions of caspase-6 in substrate-induced activation process explored by perturbation-response scanning combined with targeted molecular dynamics Comput Struct Biotechnol J. 2021 Jul 24;19:4156-4164._x000D_ 2: Graham RK, Ehrnhoefer DE, Hayden MR. Caspase-6 and neurodegeneration Trends Neurosci. 2011 Dec;34(12):646-56._x000D_ 3: Dagbay KB, Bolik-Coulon N, Savinov SN, Hardy JA. Caspase-6 Undergoes a Distinct Helix-Strand Interconversion upon Substrate Binding J Biol Chem. 2017 Mar 24;292(12):4885-4897._x000D_ 4: Vaidya S, Velzquez-Delgado EM, Abbruzzese G, Hardy JA. Substrate-induced conformational changes occur in all cleaved forms of caspase-6 J Mol Biol. 2011 Feb 11;406(1):75-91._x000D_ 5: Wang XJ, Cao Q, Zhang Y, Su XD. Activation and regulation of caspase-6 and its role in neurodegenerative diseases Annu Rev Pharmacol Toxicol. 2015;55:553-72._x000D_ 6: Velzquez-Delgado EM, Hardy JA. Phosphorylation regulates assembly of the caspase-6 substrate-binding groove Structure. 2012 Apr 4;20(4):742-51._x000D_ 7: MacPherson DJ, Mills CL, Ondrechen MJ, Hardy JA. Tri-arginine exosite patch of caspase-6 recruits substrates for hydrolysis J Biol Chem. 2019 Jan 4;294(1):71-88._x000D_ 8: Bi X, Liu X, Bi D, Sun Y. Identification of Caspase-6 and Caspase-7 from miiuy croaker and evolution analysis in fish Fish Shellfish Immunol. 2018 Dec;83:406-409._x000D_ 9: Soares J, Lowe MM, Jarstfer MB. The catalytic subunit of human telomerase is a unique caspase-6 and caspase-7 substrate Biochemistry. 2011 Oct 25;50(42):9046-55._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/20130288">10: Arnault E, Doussau M, Pesty A, Lefvre B, Courtot AM. Review: Lamin A/C, caspase-6, and chromatin configuration during meiosis resumption in the mouse oocyte Reprod Sci. 2010 Feb;17(2):102-15. </a>_x000D_ _x000D_ <strong>Products Related to Caspase-6 Substrate III Fluorogenic can be found at</strong> <a href="https://moleculardepot.com/product-category/Substrates/"> Substrates</a>