POU5F1 Antibody / OCT4
OCT4/POU5F1 is a member of the POU family of transcription factors, involved in the regulation of pluripotency during normal development and is detectable in embryonic stem and germ cells. It is a key regulator of self-renewal in embryonic stem cells; its expression is potentially correlated with tumorigenesis and can affect tumor recurrence or resistance to therapies. OCT4/POU5F1 is expressed in undifferentiated pluripotent cells, germ cells in ovary and testis.
Product Specifications
UniProt
Q01860
Reactivity
Human
Immunogen
Recombinant fragment from the human protein was used as the immunogen for the POU5F1 antibody.
Clonality
Recombinant
Clone
OCT4/6847R
Conjugation
Unconjugated
Field of Research
Stem Cell & Developmental Biology
Purification
Protein A/G affinity
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the POU5F1 antibody should be determined by the researcher.
Tested Applications
IHC-P
Host or Source
Rabbit
Preservative
0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin, 0.05% sodium azide
Isotype
Rabbit IgG, kappa
Available Sizes
Frequently Asked Questions
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