Human AADAC Protein

<strong>Human AADAC Protein</strong>_x000D_ <strong>Catalog number:</strong> B2011522_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Lyophilized_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> AADAC protein, Arylacetamide deacetylase protein, AADAC protein, Anti-AADAC protein, DAC protein, Esterase protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Hirosawa K, Fukami T, Tashiro K, Sakai Y, Kisui F, Nakano M, Nakajima M. Role of Human Arylacetamide Deacetylase (AADAC) on Hydrolysis of Eslicarbazepine Acetate and Effects of AADAC Genetic Polymorphisms on Hydrolase Activity Drug Metab Dispos. 2021 Apr;49(4):322-329._x000D_ 2: Gabriele M, Puccini P, Lucchi M, Aprile V, Gervasi PG, Longo V. Arylacetamide Deacetylase Enzyme: Presence and Interindividual Variability in Human Lungs Drug Metab Dispos. 2019 Sep;47(9):961-965._x000D_ 3: Yasuda K, Watanabe K, Fukami T, Nakashima S, Ikushiro SI, Nakajima M, Sakaki T. Epicatechin gallate and epigallocatechin gallate are potent inhibitors of human arylacetamide deacetylase Drug Metab Pharmacokinet. 2021 Aug;39:100397._x000D_ 4: Honda S, Fukami T, Hirosawa K, Tsujiguchi T, Zhang Y, Nakano M, Uehara S, Uno Y, Yamazaki H, Nakajima M. Differences in Hydrolase Activities in the Liver and Small Intestine between Marmosets and Humans Drug Metab Dispos. 2021 Sep;49(9):718-728._x000D_ 5: Fukami T, Kariya M, Kurokawa T, Iida A, Nakajima M. Comparison of substrate specificity among human arylacetamide deacetylase and carboxylesterases Eur J Pharm Sci. 2015 Oct 12;78:47-53._x000D_ 6: Uno Y, Hosokawa M, Imai T. Isolation and characterization of arylacetamide deacetylase in cynomolgus macaques J Vet Med Sci. 2015 Jun;77(6):721-4._x000D_ 7: Muta K, Fukami T, Nakajima M, Yokoi T. N-Glycosylation during translation is essential for human arylacetamide deacetylase enzyme activity Biochem Pharmacol. 2014 Jan 15;87(2):352-9._x000D_ 8: Sakai Y, Fukami T, Nagaoka M, Hirosawa K, Ichida H, Sato R, Suzuki K, Nakano M, Nakajima M. Arylacetamide deacetylase as a determinant of the hydrolysis and activation of abiraterone acetate in mice and humans Life Sci. 2021 Nov 1;284:119896._x000D_ 9: Watanabe A, Fukami T, Nakajima M, Takamiya M, Aoki Y, Yokoi T. Human arylacetamide deacetylase is a principal enzyme in flutamide hydrolysis Drug Metab Dispos. 2009 Jul;37(7):1513-20._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/26718653">10: Kurokawa T, Fukami T, Yoshida T, Nakajima M. Arylacetamide Deacetylase is Responsible for Activation of Prasugrel in Human and Dog Drug Metab Dispos. 2016 Mar;44(3):409-16. </a>_x000D_ _x000D_ <strong>Products Related to Human AADAC Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>