ZINC17167211
ZINC17167211 is a potent PPAR-α agonist (EC50=0.16 nM) that can be used in the study of diabetes, hyperlipidemia, and inflammatory diseases[1].
Product Specifications
CAS Number
592539-21-4
UNSPSC
12352005
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/zinc17167211.html
Smiles
O=C(C1=CC=CC(C2=CC=C(O2)/C=C(C3=O)\SC(N3CC(NC4=CC=C(C=C4)F)=O)=O)=C1C)O
Molecular Formula
C24H17FN2O6S
Molecular Weight
480.46
References & Citations
[1]Gangwal, et al. "Biological evaluation and structural insights for design of subtype-selective peroxisome proliferator activated receptor-α (PPAR-α) agonists." Bioorganic & Medicinal Chemistry Letters 25.2 (2015) : 270-275.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PPARα
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