Succinyl-CoA Synthetase (Highly Pure)

<strong>Succinyl-CoA Synthetase (Highly Pure)</strong>_x000D_ <strong>Catalog number:</strong> B2012603_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 29.8 kDa (α), 41.4 kDa (β)_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> SCS, Succinate Thiokinase, Succinyl Coenzyme A Synthetase_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Huang J, Fraser ME. Tartryl-CoA inhibits succinyl-CoA synthetase Acta Crystallogr F Struct Biol Commun. 2020 Jul 1;76(Pt 7):302-308._x000D_ 2: Wu B, Qiu J, Zhao TV, Wang Y, Maeda T, Goronzy IN, Akiyama M, Ohtsuki S, Jin K, Tian L, Goronzy JJ, Weyand CM. Succinyl-CoA Ligase Deficiency in Pro-inflammatory and Tissue-Invasive T Cells Cell Metab. 2020 Dec 1;32(6):967-980.e5._x000D_ 3: Huang J, Fraser ME. The structure of succinyl-CoA synthetase bound to the succinyl-phosphate intermediate clarifies the catalytic mechanism of ATP-citrate lyase Acta Crystallogr F Struct Biol Commun. 2022 Oct 1;78(Pt 10):363-370._x000D_ 4: Nishimura JS. Succinyl-CoA synthetase structure-function relationships and other considerations Adv Enzymol Relat Areas Mol Biol. 1986;58:141-72._x000D_ 5: Tong Y, Guo D, Lin SH, Liang J, Yang D, Ma C, Shao F, Li M, Yu Q, Jiang Y, Li L, Fang J, Yu R, Lu Z. SUCLA2-coupled regulation of GLS succinylation and activity counteracts oxidative stress in tumor cells Mol Cell. 2021 Jun 3;81(11):2303-2316.e8._x000D_ 6: Huang J, Nguyen VH, Hamblin KA, Maytum R, van der Giezen M, Fraser ME. ATP-specificity of succinyl-CoA synthetase from Blastocystis hominis Acta Crystallogr D Struct Biol. 2019 Jul 1;75(Pt 7):647-659._x000D_ 7: Huang J, Fraser ME. Second distinct conformation of the phosphohistidine loop in succinyl-CoA synthetase Acta Crystallogr D Struct Biol. 2021 Mar 1;77(Pt 3):357-368._x000D_ 8: Liu X, Si W, He L, Yang J, Peng Y, Ren J, Liu X, Jin T, Yu H, Zhang Z, Cheng X, Zhang W, Xia L, Huang Y, Wang Y, Liu S, Shan L, Zhang Y, Yang X, Li H, Liang J, Sun L, Shang Y. The existence of a nonclassical TCA cycle in the nucleus that wires the metabolic-epigenetic circuitry Signal Transduct Target Ther. 2021 Nov 3;6(1):375._x000D_ 9: Gomes C, Palma N, Pons MJ, Magallón-Tejada A, Sandoval I, Tinco-Valdez C, Gutarra C, Del Valle-Mendoza J, Ruiz J, Matsuoka M. Succinyl-CoA Synthetase: New Antigen Candidate of Bartonella bacilliformis PLoS Negl Trop Dis. 2016 Sep 14;10(9):e0004989._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/33174373">10: Vashisht K, Singh P, Verma S, Dixit R, Mishra N, Pandey KC. The nucleotide specificity of succinyl-CoA synthetase of Plasmodium falciparum is not determined by charged gatekeeper residues alone FEBS Open Bio. 2021 Mar;11(3):578-587. </a>_x000D_ _x000D_ <strong>Products Related to Succinyl-CoA Synthetase (Highly Pure) can be found at</strong> <a href="https://moleculardepot.com/product-category/Enzymes/"> Enzymes</a>