Sofpironium (bromide)
Product Specifications
UNSPSC Description
Sofpironium bromide (BBI 4000) is an anticholinergic agent used in the study of primary axillary hyperhidrosis (PAH). Sofpironium bromide reduces sweating by inhibiting M3 muscarinic receptors in eccrine glands at the application site. Sofpironium bromide also has a high afnity for the M1, M2, M4 and M5 subtypes[1].
Target Antigen
mAChR
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sofpironium-bromide.html
Purity
98.26
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCOC(C[N+](C)(CC1)C[C@@H]1OC([C@@](C2CCCC2)(C3=CC=CC=C3)O)=O)=O.[Br-]
Molecular Weight
470.40
References & Citations
[1]Julia Paik, et al. Sofpironium Bromide: First Approval. Drugs. 2020 Dec;80(18):1981-1986.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-109013/Sofpironium-bromide-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-109013/Sofpironium-bromide-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
1628106-94-4
Available Sizes
Curated Selection
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