Hedycoronen A
Hedycoronen A has inhibitory activity on the IL-6, IL-12 p40, and TNF-α production in LPS-Stimulated BMDCs, with IC50s of 9.1 μM, 5.6 μM, and 46.0 μM. Hedycoronen A can be isolated from Hedychium coronarium[1].
Product Specifications
CAS Number
1383441-73-3
UNSPSC
12352005
Target
Interleukin Related
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/hedycoronen-a.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@](CCC([C@@H]2/C=C/C3=CC(OC)OC3=O)=C)([H])C(C)(CCC1)C
Molecular Formula
C21H30O3
Molecular Weight
330.46
References & Citations
[1]Kiem PV, et al. Labdane-type diterpenoids from the rhizomes of Hedychium coronarium inhibit lipopolysaccharide-stimulated production of pro-inflammatory cytokines in bone marrow-derived dendritic cells. Chem Pharm Bull (Tokyo) . 2012;60 (2) :246-50.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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