LIMA1 Antibody / EPLIN

LIM domain and actin-binding protein 1, also called EPLIN (Epithelial protein lost in neoplasm), is a protein that in humans is encoded by the LIMA1 gene. This gene encodes a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles. It is downregulated in some cancer cell lines. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and expression of some of the variants maybe independently regulated.