EXO1 Antibody / Exonuclease 1
Exonuclease 1 is an enzyme that in humans is encoded by the EXO1 gene. It is mapped to 1q43. This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunofluorescence: 5 µg/mL, Immunoprecipitation: 2ug/500ug of lysate, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q9UQ84
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human protein (amino acids Q25-Q846) was used as the immunogen for the EXO1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IF, IP, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
Limitations
This EXO1 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the EXO1 antibody should be determined by the researcher.
Location
Nuclear
Image Legend
Frequently Asked Questions
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