CFTR corrector 16

CFTR corrector 16 (Compound 39) is a corrector for cystic fibrosis transmembrane conductance regulator (CFTR), that can be used in research of cystic fibrosis disease[1].

Product Specifications

CAS Number

[1210305-23-9]

UNSPSC

12352005

Target

CFTR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/cftr-corrector-16.html

Smiles

O=C(C1(C2=CC=C(Cl)C=C2)CCCC1)NC3=CC(C4=CC=CS4)=NN3C(N5)=NC6=C(CCCC6)C5=O

Molecular Formula

C27H26ClN5O2S

Molecular Weight

520.05

References & Citations

[1]Vaccarin C, et al., Synthesis and Biological Evaluation of Pyrazole-Pyrimidones as a New Class of Correctors of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) . J Med Chem. 2024 Aug 22;67 (16) :13891-13908.